Intracytoplasmic Sperm Injection (ICSI) : In the history of fertility medicine, one of the most significant breakthroughs was the development of a process called intracytoplasmic sperm injection, or ICSI for short in 1990s. This technique was developed by G. Palermo at Brussel .If there is male factor infertility and the couple is going through in vitro fertilization (IVF), then ICSI is a better procedure. It has revolutionized the treatment of male infertility as it allows couples to achieve fertilization even when only a few sperm are available. .
Fertilization rates of 70-80% (of all eggs injected) equivalent to that of fertilization with normal sperm are currently being achieved, and pregnancy rates are comparable to those seen with IVF in couples with no male factor infertility
There are some risks to using ICSI with IVF. For instance: ICSI can damage healthy eggs during the process. ICSI & IVF increases the risk of becoming pregnant with multiples. Some theorize that there is a greater chance for genetic syndromes or birth defects following procedures like ICSI that manipulate sperm and eggs.However, this risk is minimal..