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Effect of age  

Age related infertility remains  one of the   most difficult challenges of infertility treatment . Reproductive specialists have known for years that the pregnancy rate is inversely related to the female partner's age . Current social trend of  women  to  delay childbearing for educational and career goals, have a dramatic increase in age related infertility . Delayed child bearing is becoming increasingly common in our  society  like west for example,  many couples prefer to rear their children only after establishing  a  stable relationship , financial security , also , because of  increasing numbers  of  late and second   marriages .      

 
As a woman's age increases , her ability to become pregnant  decreases due to the many biological changes taking place in her body . The real issue the quality and quantity of the egg  which translates into embryo quality finally .


From age 30 to 35 , the chances of becoming pregnant gradually decline and after age 40 there is a sharp decline . Even if a woman becomes pregnant at a later age , chances of  miscarriage  and chromosomal  abnormalities , resulting in birth defects such as Down's Syndrome ,  increases  with age . Assisted reproductive technologies, including in vitro fertilization  and  intracytoplasmic  sperm injection ,  also become less successful as age increases.   Furthermore ,  advanced maternal age is associated with  increased risk of  gestational diabetes ,  pre-eclampsia ,  placenta praevia ,  caesarean section , fetal growth restriction ,   premature birth and the   risk of stillbirth .   Also the   possibility   of premature     menopause and    gynecological      problems such as tubal damage endometriosis ,    fibroids  also tend to affect the fertility .


Men can remain fertile for much longer than women . Even though male fertility also declines with age , it tends to happen gradually for men . While many men remain fertile into their 50s and beyond , the proportion of men with sperm disorders increases with age . The decline in male fertility is more gradual for men than women .